The below article is a topic that I think should be on the minds of every individual as we ponder why so many animal are getting cancer and they are getting sicker and sicker. As a veterinarian for over 35 years I am seeing more chronically ill animals that cannot be cured as their immune systems that have failed. We are seeing this in younger and younger animals as cancer affects over 46% of dogs and 39 % of cats. The frustration that veterinarians and their caretakers feel is overwhelming. Owners ask Why? and Why can’t we help them? We are getting epigenetic damage from many of the 80,000 chemicals that are in our environment that were not there 60 years ago.
Those of us that work in holistic veterinary medicine are trying to find ways to keep these tragic failures of the health of these individual animals. As we look at the research that is in the below and now we can see that all the pesticides, toxins and unnecessary vaccinations that we have given our pets for generation after generation have done damage that has changed the genes of those pets. What our dogs grandmother got exposed to can affect multiple generations to come. Sicker and sicker, younger and younger until it is so obvious.
We all need to start to wake up and start to question all the chemicals we put on our lawns, clean our homes, spray or spot on our pets. You are what you eat and those chemical will transfer their damage to your DNA too. The animals we bring into our homes are the canaries in the coal mine. They are showing us what the future of our human family members will be. In 12 years we can see 6 generations of pets and genetic breakdown can be right in front of our face…Lets wake up and try to stop further damage and help our beloved family members more protected from toxic chemicals and environmental damage.
I say these words as a frustrated veterinarian questioning the massive numbers of cancer that come into my practice. We try to boost the immune system and try to support the healthy cells and organs so they can resist the DNA damage. We hope to make more quality life and more quality time with these very important family members.
You can hear the audio of a discussion on this paper Epigenetic transgenerational inheritance of altered stress responses
David Crewsa,1,2, Ross Gillettea, Samuel V. Scarpinoa, Mohan Manikkamb, Marina I. Savenkovab, and Michael K. Skinnerb,1,2
Section of Integrative Biology, University of Texas at Austin, Austin, TX 78712; and
bCenter for Reproductive Biology, School of Biological Sciences, Washington State University, Pullman, WA 99164
Edited by Fred H. Gage, The Salk Institute, San Diego, CA, and approved April 18, 2012 (received for review November 15, 2011)
Ancestral environmental exposures have previously been shown to promote epigenetic transgenerational inheritance and influence all aspects of an individual’s life history. In addition, proximate life events such as chronic stress have documented effects on the development of physiological, neural, and behavioral phenotypes in adulthood. We used a systems biology approach to investigate in male rats the interaction of the ancestral modifications carried transgenerationally in the germ line and the proximate modifications involving chronic restraint stress during adolescence. We find that a single exposure to a common-use fungicide (vinclozolin) three generations removed alters the physiology, behavior, metabolic activity, and transcriptome in discrete brain nuclei in descendant males, causing them to respond differently to chronic restraint stress. This alteration of baseline brain development promotes a change in neural genomic activity that correlates with changes in physiology and behavior, revealing the interaction of genetics, environment, and epigenetic transgenerational inheritance in the shaping of the adult phenotype. This is an important demonstration in an animal that ancestral exposure to an environmental compound modifies how descendants of these progenitor individuals perceive and respond to a stress challenge experienced during their own life history.